Simultaneous determination of salbutamol sulphate and bromhexine hydrochloride in tablets by reverse phase liquid chromatography

Simultaneous Determination of Salbutamol Sulphate and Bromhexine Hydrochloride in Tablets by Reverse Phase Liquid Chromatography

A simple reverse phase liquid chromatographic method has been developed and subsequently validated for simultaneous determination of salbutamol sulphate and bromhexine hydrochloride. The separation was carried out using a mobile phase consisting of acetonitrile, methanol and phosphate buffer, pH 4 in the ratio 60:20:20 v/v. The column used was SS Wakosil-II C-18 with a flow rate of 1 ml/min and...

Stability-indicating HPLC Method for Simultaneous Determination of Terbutaline Sulphate, Bromhexine Hydrochloride and Guaifenesin

The aim of the present study was the development and subsequent validation of a simple, precise and stability-indicating reversed phase HPLC method for the simultaneous determination of guaifenesin, terbutaline sulphate and bromhexine hydrochloride in the presence of their potential impurities in a single run. The photolytic as well as hydrolytic impurities were detected as 3,5-dihydroxybenzoic...

Thin Layer Chromatodraphy Method for the Determination of Ternary Mixture Containing Salbutamol Sulphate, Bromhexine Hydrochloride and Etofylline

Simple, rapid, accurate, precise, reliable and economical thin layer chromatographic and spectrophotometric methods have been proposed for the resolution and determination of Salbutamol sulphate (SS), Brombexine hydrochloride (BH) and Etofylline (ET) in pure and pharmaceutical formulations respectively. The developed methods show best results in terms of resolution, linearity, accuracy, precisi...

Simultaneous determination of Sitagliptin phosphate monohydrate and Metformin hydrochloride in tablets by validated ultra performance liquid Chromatography Method

Simultaneous Determination of Ondansetron Hydrochloride and Omeprazole in Tablets by Planar Chromatography

A new simple, precise and selective high performance thin layer chromatographic (HPTLC) method has been developed and validated for simultaneous determination of ondansetron hydrochloride and omeprazole in tablets. Identification and determination were performed on 20 cm × 10 cm aluminium-backed TLC plates, coated with 0.2 mm layers of silica gel 60 F254, previously washed with methanol. Ethyl ...